12 research outputs found
Transient fault behavior in a microprocessor: A case study
An experimental analysis is described which studies the susceptibility of a microprocessor based jet engine controller to upsets caused by current and voltage transients. A design automation environment which allows the run time injection of transients and the tracing from their impact device to the pin level is described. The resulting error data are categorized by the charge levels of the injected transients by location and by their potential to cause logic upsets, latched errors, and pin errors. The results show a 3 picoCouloumb threshold, below which the transients have little impact. An Arithmetic and Logic Unit transient is most likely to result in logic upsets and pin errors (i.e., impact the external environment). The transients in the countdown unit are potentially serious since they can result in latched errors, thus causing latent faults. Suggestions to protect the processor against these errors, by incorporating internal error detection and transient suppression techniques, are also made
Capacités d'adaptation des exploitations laitières des hautes terres de la province du Vakinankaratra à Madagascar : impacts de la crise de 2009
L'objectif de l'étude a été de comprendre les pratiques des exploitants laitiers malgaches après la crise économique (et politique) de 2009, ainsi que d'évaluer son impact sur les revenus des exploitations. L'analyse a été centrée sur les stratégies d'adaptation des éleveurs laitiers pour maintenir le revenu de leurs exploitations face cette période de crise. Elle s'est basée sur des enquêtes réalisées entre 2008 et 2010. Les données ont porté sur trois zones représentant la diversité du triangle laitier des hautes terres, principale région productrice de lait de Madagascar. Une typologie a été réalisée dans un premier temps sur un échantillon de 59 exploitations pour comprendre la rationalité des pratiques d'élevage, en particulier l'alimentation des animaux. Dans un second temps, une modélisation économique avec le logiciel Olympe s'est appuyée sur 21 d'entre elles pour estimer l'impact de la crise sur les revenus des producteurs laitiers. Des scénarios prospectifs rendant compte de l'efficience et des risques des choix techniques par les exploitants ont permis d'explorer l'évolution de la situation avant et après la crise, et de montrer une certaine résilience des exploitations. (Résumé d'auteur
Area selection for diamonds using magnetotellurics : examples from southern Africa
Author Posting. © Elsevier B.V., 2009. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Lithos 112 (2009): 83-92, doi:10.1016/j.lithos.2009.06.011.Southern Africa, particularly the Kaapvaal Craton, is one of the world’s best natural
laboratories for studying the lithospheric mantle given the wealth of xenolith and seismic data
that exist for it. The Southern African Magnetotelluric Experiment (SAMTEX) was launched
to complement these databases and provide further constraints on physical parameters and
conditions by obtaining information about electrical conductivity variations laterally and with
depth. Initially it was planned to acquire magnetotelluric data on profiles spatially coincident
with the Kaapvaal Seismic Experiment, however with the addition of seven more partners to
the original four through the course of the experiment, SAMTEX was enlarged from two to
four phases of acquisition, and extended to cover much of Botswana and Namibia. The
complete SAMTEX dataset now comprises MT data from over 675 distinct locations in an
area of over one million square kilometres, making SAMTEX the largest regional-scale MT
experiment conducted to date.
Preliminary images of electrical resistivity and electrical resistivity anisotropy at 100
km and 200 km, constructed through approximate one-dimensional methods, map resistive
regions spatially correlated with the Kaapvaal, Zimbabwe and Angola Cratons, and more
conductive regions spatially associated with the neighbouring mobile belts and the Rehoboth
Terrain. Known diamondiferous kimberlites occur primarily on the boundaries between the
resistive or isotropic regions and conductive or anisotropic regions.
Comparisons between the resistivity image maps and seismic velocities from models
constructed through surface wave and body wave tomography show spatial correlations
between high velocity regions that are resistive, and low velocity regions that are conductive.
In particular, the electrical resistivity of the sub-continental lithospheric mantle of the
Kaapvaal Craton is determined by its bulk parameters, so is controlled by a bulk matrix
property, namely temperature, and to a lesser degree by iron content and composition, and is
not controlled by contributions from interconnected conducting minor phases, such as
graphite, sulphides, iron oxides, hydrous minerals, etc. This makes quantitative correlations
between velocity and resistivity valid, and a robust regression between the two gives an
approximate relationship of Vs [m/s] = 0.045*log(resistivity [ohm.m]).We especially thank our
academic funding sponsors; the Continental Dynamics programme of the U.S. National
Science Foundation, the South African Department of Science and Technology, and Science
Foundation Ireland
Congenital Diarrhea and Cholestatic Liver Disease: Phenotypic Spectrum Associated with MYO5B Mutations
Myosin Vb (MYO5B) is a motor protein that facilitates protein trafficking and recycling in polarized cells by RAB11- and RAB8-dependent mechanisms. Biallelic MYO5B mutations are identified in the majority of patients with microvillus inclusion disease (MVID). MVID is an intractable diarrhea of infantile onset with characteristic histopathologic findings that requires life-long parenteral nutrition or intestinal transplantation. A large number of such patients eventually develop cholestatic liver disease. Bi-allelic MYO5B mutations are also identified in a subset of patients with predominant early-onset cholestatic liver disease. We present here the compilation of 114 patients with disease-causing MYO5B genotypes, including 44 novel patients as well as 35 novel MYO5B mutations, and an analysis of MYO5B mutations with regard to functional consequences. Our data support the concept that (1) a complete lack of MYO5B protein or early MYO5B truncation causes predominant intestinal disease (MYO5B-MVID), (2) the expression of full-length mutant MYO5B proteins with residual function causes predominant cholestatic liver disease (MYO5B-PFIC), and (3) the expression of mutant MYO5B proteins without residual function causes both intestinal and hepatic disease (MYO5B-MIXED). Genotype-phenotype data are deposited in the existing open MYO5B database in order to improve disease diagnosis, prognosis, and genetic counseling.This research was funded by Jubiläumsfonds der Österreichischen Nationalbank, grant no.16678 (to A.R.J.), grant no. 18019 (to G.-F.V.) and Tiroler Wissenschaftsfonds, grant No. 0404/2386 (toG.-F.V.).info:eu-repo/semantics/publishedVersio
Transient Fault Behavior in a Microprocessor: A Case Study
Coordinated Science Laboratory was formerly known as Control Systems LaboratoryNASA / NASA NAG 1-602Semiconductor Research Corporation / 88-DP-109U of I OnlyRestricted to UIUC communit
Congenital Diarrhea and Cholestatic Liver Disease: Phenotypic Spectrum Associated with MYO5B Mutations
Myosin Vb (MYO5B) is a motor protein that facilitates protein
trafficking and recycling in polarized cells by RAB11- and
RAB8-dependent mechanisms. Biallelic MYO5B mutations are identified in
the majority of patients with microvillus inclusion disease (MVID). MVID
is an intractable diarrhea of infantile onset with characteristic
histopathologic findings that requires life-long parenteral nutrition or
intestinal transplantation. A large number of such patients eventually
develop cholestatic liver disease. Bi-allelic MYO5B mutations are also
identified in a subset of patients with predominant early-onset
cholestatic liver disease. We present here the compilation of 114
patients with disease-causing MYO5B genotypes, including 44 novel
patients as well as 35 novel MYO5B mutations, and an analysis of MYO5B
mutations with regard to functional consequences. Our data support the
concept that (1) a complete lack of MYO5B protein or early MYO5B
truncation causes predominant intestinal disease (MYO5B-MVID), (2) the
expression of full-length mutant MYO5B proteins with residual function
causes predominant cholestatic liver disease (MYO5B-PFIC), and (3) the
expression of mutant MYO5B proteins without residual function causes
both intestinal and hepatic disease (MYO5B-MIXED). Genotype-phenotype
data are deposited in the existing open MYO5B database in order to
improve disease diagnosis, prognosis, and genetic counseling